Transplant Benefit Calculator

 

IMPORTANTE: separare i decimali con il punto non con la virgola (separate decimals with point not comma)

 

PARAMETRI CANDIDATO

Creatinine / Creatinina (mg/dL) 

Bilirubin / Bilirubina (mg/dL) 

INR 

Serum AFP /  Alfafetoproteina (ng/mL) 

Maximum tumor size / Diametro massimo (cm) 

 

 

 

Donor Age

ETA' DONATORE

Anni (years)

 

 

 

 

 

SCORE

MELD (1)

% DROP-OUT Probablity at 90 DAYS of non-HCC patients (1)

% DROP-OUT Probability at 90 DAYS of HCC patients (2)

D-MELD (3)

% PROBABILITY OF DEATH at 90 DAYS AFTER TRANSPLANT (3)

TRANSPLANT BENEFIT OF NON-HCC PATIENTS

TRANSPLANT BENEFIT OF HCC PATIENTS
PREDICTED SURVIVAL (3)   1-year   3-years    5-years 

 

Sopravvivenza per D-MELD nei trapiantati in Italia (Post-transplant survival by D-MELD and covariates in an Italian cohort)  

 

MELD-based formula

 

MELD (1) 9.57 x ln (creatinine(mg/dL)) + 3.78 x ln (bilirubin(mg/dL)) + 11.2 x ln(INR) + 6.43
HCC-MELD (2) 1 - 0.92e(0.09369 x (MELD Score - 12.48) + 0.1505 x (Tumor Size in cm - 2.59) + 0.00193 x (Serum AFP in ng/mL - 97.4))
D-MELD (3) Donor Age (years) * MELD Score

 

Bibliografia

1) Wiesner RH, McDiarmid SV, Kamath PS.MELD and PELD: application of survival models to liver allocation, Liver Transpl 2001;7:567–80

2) Freeman RB, Edwards EB, Harper AM. Waiting list removal rates among patients with chronic and malignant liver diseases. Am J Transplant. 2006;6:1416-21.

3) Halldorson JB, Bakthavatsalam R, Fix O. D-MELD, a simple predictor of post liver transplant mortality for optimization of donor/recipient matching. Am J Transplant. 2009;9:318-26.

 

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